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Anti-CD263 / TRAIL-R3 Monoclonal Antibody (Clone:TRAIL-R3-02) -Azide free

TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5) .

Product Specifications

Product Name Alternative

TNFRSF10C||DCR1||LIT||TRAILR3||TRID||UNQ321/PRO366

Gene Name

TNFRSF10C

Gene ID

8794

UniProt

O14798

Host

Mouse

Reactivity

Human

Immunogen

TRAIL-R3 (aa 1-280) - hIgGhc fusion protein

Target Antigen

CD263 / TRAIL-R3

Clonality

Monoclonal

Clone

TRAIL-R3-02

Applications

FACS

Purification

Purified by protein-A affinity chromatography

Format

Azide free

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Recommended dilution:1-5 μg/mL

Isotype

Mouse IgG1

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