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Anti-CD90.2 / Thy-1.2 Monoclonal Antibody (Clone:1aG4/C5) -Azide free

CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. In the mouse, CD90 is expressed mainly on thymocytes and peripheral T lymphocytes. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.

Product Specifications

Product Name Alternative

Thy-1 antigen, Thy1, Thy-1

Gene Name

Thy1

Gene ID

21838

UniProt

P01831

Host

Mouse

Reactivity

Mouse

Immunogen

Thymocytes from C3H/Di mice (Thy-1.2 positive)

Target Antigen

CD90.2 / Thy-1.2 (mouse)

Clonality

Monoclonal

Clone

1aG4/C5

Applications

FACS, WB, ICC, Functional Assay

Purification

Purified by protein-A affinity chromatography

Format

Azide free

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Recommended dilution: 1 μg/mL Western Blotting Immunocytochemistry Functional Application The bound of antibody 1aG4/C5 to the transfected mast cells induces the activation processes which are similar, but not identical, to the antigen activation of IgE stimulated cells. Other studies approve that the antibody 1aG4/C5 precipitates complexes with Lyn protein tyrosine kinase.

Isotype

Mouse IgG3

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