Anti-CD59 / Protectin Monoclonal Antibody (Clone:MEM-129) -Azide free
CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC) . It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
Product Specifications
Product Name Alternative
CD59||MIC11||MIN1||MIN2||MIN3||MSK21
Gene Name
CD59
Gene ID
966
UniProt
P13987
Host
Mouse
Reactivity
Human
Immunogen
Human peripheral blood lymphocytes
Target Antigen
CD59
Clonality
Monoclonal
Clone
MEM-129
Applications
Functional Assay
Purification
Purified by precipitation and chromatography
Format
Purified
Components
Concentration: 1 mg/mL Formulation : Tris buffered saline (TBS), pH 8.0
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Functional Application The antibody MEM-129 activates T cells. Flow Cytometry Recommended dilution:2-8 μg/mL
Isotype
Mouse IgM
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