Polyclonal antibody to TRAIP (TRIP)
TRIP (TRAF-interacting protein), also known as TRAIP is a component of receptor-TRAF signaling complexes. Structurally it contains an N-terminal RING finger motif and a putative coiled-coil domain and composed of 469amino acid approximately. TRIP has been shown to associate with TRNFR2 or CD30 signaling complexes through its interaction with TRAF proteins and inhibit TRAF2-mediated NF-kB activation. The recruitment of different TRAFs and TRAF associated proteins like TRIP to receptor complexes can help regulate and provide specificity to the intracellular signals triggered by the cell surface receptors.
Product Specifications
Product Name Alternative
TRAIP||RNF206||TRIP
Gene Name
TRAIP
Gene ID
10293
UniProt
Q9BWF2
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human TRIP (amino acids 294-313 ESPAPVEVNLKLRRPSFRDD) was used as immunogen for this antibody
Target Antigen
TRAIP (TRIP)
Clonality
Polyclonal
Applications
IP, IHC, WB
Format
Sera
Components
50 μl sera
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
WB: 1:1000-1:2000, IHC (paraffin) : 1:1000-1:5000, IHC (frozen) : Users should optimize, IP: 1:50-1:200
Isotype
Rabbit IgG
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