Polyclonal antibody to Mouse TRAF-1
This antibody recognizes TRAF1. Mouse TRAF1 is a 409 amino acid protein.TRAF1 is a member of TRAF (TNF receptor-associated factor) adapter proteins composed 416 amino acids. The members of this family link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases. TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. TRAFs also interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.
Product Specifications
Product Name Alternative
TNF receptor-associated factor 1
Gene Name
Traf1
Gene ID
22029
UniProt
P39428
Host
Rabbit
Reactivity
Mouse
Immunogen
A synthetic peptide of mouse TRAF-1 (amino acids 51-69 CRADNLHPVSPGSPLTQEK) was used as immunogen for this antibody
Target Antigen
TRAF-1
Clonality
Polyclonal
Applications
IP, IHC, WB
Format
Sera
Components
50 μl sera
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
WB: 1:1000-1:2000, IHC (paraffin) : 1:1000-1:5000, IHC (frozen) : Users should optimize, IP: 1:50-1:200
Isotype
Rabbit IgG
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