Polyclonal antibody to NALP4 (PAN-2)
This antibody recognizes NALP4; human NALP4 is a 994 amino acid protein. NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD) . NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
Product Specifications
Product Name Alternative
NLRP4||NALP4||PAN2||PYPAF4||RNH2
Gene Name
NLRP4
Gene ID
147945
UniProt
Q96MN2
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human NALP4/PAN2/PYPAF4 (amino acids 139-157 FAPKETGKQPRTVIIQGPQ) was used as immunogen for this antibody
Target Antigen
NALP4 (PAN-2)
Clonality
Polyclonal
Applications
IP, IHC, WB
Format
Sera
Components
50 μl sera
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
WB: 1:1000-1:2000, IHC (paraffin) : 1:1000-1:5000, IHC (frozen) : Users should optimize, IP: 1:50-1:200
Isotype
Rabbit IgG
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
