Polyclonal antibody to ITRAF
TANK/I-TRAF has also been shown to bind to other proteins in the NF-kB signaling pathway, including NEMO.This antibody recognizes TANK/I-TRAF, human TANK/I-TRAF is 425 amino acid protein.These families of proteins are associated with and transduce signals from members of the tumor necrosis factor receptor (TNFR) superfamily. TANK/I-TRAF (TRAF family member associated NF-kB activator/TRAF-interacting protein) that was first defined as a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. The TANK/I-TRAF is thought to inhibit TRAF function by sequestering the TRAFs in the cytoplasm, thereby blocking their recruitment to the TNFR.
Product Specifications
Product Name Alternative
TANK||ITRAF||TRAF2
Gene Name
TANK
Gene ID
10010
UniProt
Q92844
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human ITRAF (amino acids 346-367 DPSDAPFPSLDSPGKAIRGPQQ) was used as immunogen for this antibody
Target Antigen
ITRAF
Clonality
Polyclonal
Applications
IP, IHC, WB
Format
Sera
Components
50 μl sera
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
WB: 1:1000-1:2000, IHC (paraffin) : 1:1000-1:5000, IHC (frozen) : Users should optimize, IP: 1:50-1:200
Isotype
Rabbit IgG
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