Polyclonal antibody to ITRAF

TANK/I-TRAF has also been shown to bind to other proteins in the NF-kB signaling pathway, including NEMO.This antibody recognizes TANK/I-TRAF, human TANK/I-TRAF is 425 amino acid protein.These families of proteins are associated with and transduce signals from members of the tumor necrosis factor receptor (TNFR) superfamily. TANK/I-TRAF (TRAF family member associated NF-kB activator/TRAF-interacting protein) that was first defined as a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. The TANK/I-TRAF is thought to inhibit TRAF function by sequestering the TRAFs in the cytoplasm, thereby blocking their recruitment to the TNFR.