Anti-P. falciparum, HRP-2 (PFAL-2440)

Specificity: Anti-P. falciparum (Clone PFAL-7871) is specific for the Histidine rich protein II of P. falciparum. Background: Plasmodium is a genus of parasitic protozoa that causes the disease malaria, a significant global health concern. There are several species of Plasmodium that can infect humans with the most common being P. falciparum, P. vivax, P. malariae, and P. ovale. The parasite is transmitted by the bite of infected female Anopheles mosquitoes. Once inside the host, the parasite infects and multiplies within red blood cells. HRP-2 is a protein released by Plasmodium falciparum into the bloodstream when it infects red blood cells. It is unique to P. falciparum and has become an important target for diagnostics, especially rapid diagnostic testing.

Product Specifications

Product Name Alternative

Histidine rich protein II, HRP-2, pf-HRP-2, Malaria

Host

Mouse

Target Antigen

HRP-2

Clonality

Monoclonal

Clone

PFAL-2440

Applications

ELISA

Purification

Purity: >=90% Preparation: This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.

Components

Concentration: >=1.0 mg/mL Formulation: Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.