Tick-Borne Encephalitis Virus, NS1 (Clone TBEV-5692)

Specificity: Anti-Tick-Borne Encephalitis Virus (Clone TBEV-5692) is specific for the non-structural protein 1 (NS1) from Tick-Borne Encephalitis Virus. There is no cross-reactivity with other Flavivirus. Background: Tick-borne encephalitis virus (TBEV) is a single-stranded RNA virus that is a member of the Flaviviridae family within the genus Flavivirus. The virus is primarily transmitted to humans through the bite of infected ticks, with Ixodes ricinus and Ixodes persulcatus being the main vectors. TBEV is categorized into three subtypes: European, Siberian, and Far Eastern. The virus causes tick-borne encephalitis (TBE), a viral neurological disease characterized by fever, headache, and, in severe cases, inflammation of the brain. The disease burden of TBE varies geographically, with endemic regions in parts of Europe, Asia, and Russia. TBE poses a significant public health concern, and vaccination campaigns have been implemented in endemic areas to mitigate the impact of this potentially severe and sometimes fatal disease.