Anti-West Nile Virus, NS1 (Clone WNV-3223)

Specificity: Anti-West Nile virus (Clone WNV-3223) is specific for WNV non-structural protein 1 (NS1) . There is no cross-reactivity with other Flavivirus. Background: West Nile Virus (WNV) is a mosquito-borne, enveloped, positive-stranded RNA flavivirus1. Flavivirus nonstructural protein NS1 has been proposed as an antibody target to avoid antibody-dependent enhancement2. NS1 is a 46-55 kDa glycoprotein that is expressed as a dimer on the cell surface and as a soluble hexamer in the extracellular space and in circulation during infection. WNV NS1 dimer consists of a ÃŸ-roll, wing, and ÃŸ-ladder.

Product Specifications

Product Name Alternative

NS1, Non-structural protein 1, WNV

Host

Mouse

Clonality

Monoclonal

Clone

WNV-3223

Applications

ELISA

Purification

Purity: ≥90% by SDS PAGE Preparation: This monoclonal antibody is purified by ion exchange chromatography.

Components

Concentration: ≥1.0 mg/mL Formulation: Formulated in 0.015 M phosphate buffered saline (0.85% NaCl), pH 7.2 and contains 0.05% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.