Anti-Salmonella sp., LPS core (SAL-2683)

Specificity: Anti-Salmonella (Clone SAL-2683) is specific for the common LPS core of all Salmonella O-serogroups tested (A, B, C1, C2, D, E1, E3, E4, F, G1, G2) but negative for E. coli, Klebsiella, Citrobacter, Pseudomonas, Yersinia, Shigella, Proteus & Legionella. Background: Salmonella is a diverse group of Gram-negative bacteria known for causing a wide range of gastrointestinal illnesses in humans and animals. Salmonella infections, termed salmonellosis, can lead to symptoms such as diarrhea, abdominal cramps, fever, and vomiting. The bacteria possess a complex outer membrane, which includes lipopolysaccharides (LPS) that play a crucial role in interactions with the host immune system. Salmonella serotypes, characterized by variations in their LPS and other surface antigens, are used for strain differentiation. Certain serotypes like Salmonella Typhi and Salmonella Paratyphi are responsible for causing typhoid and paratyphoid fevers, respectively, while others, including Salmonella Enteritidis and Salmonella Typhimurium, are common causes of foodborne illnesses.