Anti-Powassan Virus, NS1 (Clone POWV-6117)

Specificity: Anti-Powassan Virus (Clone POWV-6117) is specific for the non-structural protein 1 (NS1) from Powassan Virus. Background: Powassan virus (POWV) is a single-stranded RNA virus that is a member of the Flaviviridae family within the genus Flavivirus. This virus is transmitted to humans primarily through the bite of infected ticks, particularly Ixodes scapularis and Ixodes cookei. Powassan virus is classified into two distinct lineages: the Powassan (POWV) lineage and the deer tick virus (DTV) lineage. Powassan virus infection can result in severe neurological symptoms, including encephalitis and meningitis. While the overall disease burden is relatively low compared to other tick-borne illnesses, the virus has gained attention due to its potential for rapid onset of severe illness and its association with fatal outcomes. Powassan virus is primarily distributed in North America and parts of Russia, and its emergence and the increasing incidence of cases underscore the importance of continued surveillance and research for understanding its epidemiology and potential public health impact.