Biotinylated Anti-GPNMB antibody (11G4), IgG1 Chimeric mAb
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Product Name Alternative
HGFIN; NMB; PLCA3
Gene Name
GPNMB
UniProt
Q14956
Host
Rabbit
Reactivity
Human
Target Antigen
GPNMB
Clonality
Monoclonal
Clone
11G4
Applications
FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.
Applications Notes
Flow Cyt 1/100
Isotype
IgG1
Frequently Asked Questions
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