Biotinylated Anti-EGFRVIII antibody (2E12) ; IgG1 Chimeric mAb
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Product Specifications
Product Name Alternative
EGFR; RBB; RBB1; ER1; IG61; ENA
Gene Name
EGFRVIII
UniProt
P00533
Host
Rabbit
Reactivity
Human
Target Antigen
EGFRVIII
Clonality
Monoclonal
Clone
2E 12
Applications
FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.
Applications Notes
Flow Cyt 1/100
Isotype
IgG1
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