Biotinylated Anti-CXCR4 antibody (DMC680), IgG1 Chimeric mAb

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts; hypogammaglobulinemia; infections; and myelokathexis) syndrome. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. [provided by RefSeq; Jul 2008]

Product Specifications

Product Name Alternative

CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS

Gene Name

CXCR4

UniProt

P61073; A0A0U3FJG0; A0A0U3GXA9

Host

Rabbit

Reactivity

Human

Target Antigen

CXCR4

Clonality

Monoclonal

Clone

DMC680

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.