Biotinylated Anti-YAP1 antibody (DMC495) ; IgG1 Chimeric mAb
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development; growth; repair; and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Specifications
Product Name Alternative
COB1; YAP; YAP2; YAP65; YKI
Gene Name
YAP1
UniProt
P46937
Host
Rabbit
Reactivity
Human
Target Antigen
YAP1
Clonality
Monoclonal
Clone
DMC495
Applications
FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.
Applications Notes
Flow Cyt 1:100
Isotype
IgG1
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