Biotinylated Anti-CXCR3 antibody (DM208) ; Rabbit mAb

This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9:Mig (monokine induced by interferon-g) ; CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4:PF4 (PMID:12782716) . [provided by RefSeq; Jun 2011]

Product Specifications

Product Name Alternative

CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR

Gene Name

CXCR3

UniProt

P49682

Host

Rabbit

Reactivity

Human

Target Antigen

CXCR3

Clonality

Monoclonal

Clone

DM208

Applications

ELISA; FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.