Biotinylated Anti-PD-1 antibody (DM177) ; Rabbit mAb

This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice; expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB:c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Product Specifications

Product Name Alternative

PDCD1; PD1; CD279; SLEB2

Gene Name

PD-1

UniProt

Q15116

Host

Rabbit

Reactivity

Human

Target Antigen

PD-1

Clonality

Monoclonal

Clone

DM177

Applications

ELISA; FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.