Biotinylated Anti-PD-1 antibody (DM177) ; Rabbit mAb
This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice; expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB:c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Product Specifications
Product Name Alternative
PDCD1; PD1; CD279; SLEB2
Gene Name
PD-1
UniProt
Q15116
Host
Rabbit
Reactivity
Human
Target Antigen
PD-1
Clonality
Monoclonal
Clone
DM177
Applications
ELISA; FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.
Applications Notes
ELISA 1:5000-10000; FACS 1:100
Isotype
IgG
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