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Biotinylated Anti-CD10 antibody (DM176) ; Rabbit mAb

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL) . The encoded protein is present on leukemic cells of pre-B phenotype; which represent 85% of cases of ALL. This protein is not restricted to leukemic cells; however; and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon; enkephalins; substance P; neurotensin; oxytocin; and bradykinin.

Product Specifications

Product Name Alternative

MME; CALLA; CD10; DKFZp686O16152; MGC126681; MGC126707; NEP; SFE; Neprilysin

Gene Name

CD10

UniProt

P08473

Host

Rabbit

Reactivity

Human

Target Antigen

CD10

Clonality

Monoclonal

Clone

DM176

Applications

ELISA; FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

ELISA 1:5000-10000; FACS 1:100

Isotype

IgG

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