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Biotinylated Anti-MICB antibody (DM168) ; Rabbit mAb

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells; CD8 alphabeta T cells; and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however; it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Product Specifications

Product Name Alternative

MIC-B; PERB11.2

Gene Name

MICB

UniProt

Q29980

Host

Rabbit

Reactivity

Human

Target Antigen

MICB

Clonality

Monoclonal

Clone

DM168

Applications

ELISA; FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

ELISA 1:5000-10000; FACS 1:100

Isotype

IgG

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