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Biotinylated Anti-NTB-A antibody (DM159) ; Rabbit mAb

The protein encoded by this gene is a type I transmembrane protein; belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK) ; T; and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Product Specifications

Product Name Alternative

NTB-A; SLAMF6; Ly108; NK-T-B-antigen; CD352; KALI

Gene Name

NTB-A

UniProt

Q96DU3

Host

Rabbit

Reactivity

Human

Target Antigen

NTB-A

Clonality

Monoclonal

Clone

DM159

Applications

ELISA; FACS; WB; IHC

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

ELISA 1:5000-10000; FACS 1:100; WB 1:1000; IHC 1:100

Isotype

IgG

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