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Biotinylated Anti-CD30 antibody (DM105) ; Rabbit mAb

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated; but not by resting; T and B cells. TRAF2 and TRAF5 can interact with this receptor; and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis; and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Product Specifications

Product Name Alternative

TNFRSF8; CD30; D1S166E; Ki-1

Gene Name

CD30

UniProt

P28908

Host

Rabbit

Reactivity

Human

Target Antigen

CD30

Clonality

Monoclonal

Clone

DM105

Applications

ELISA; FACS; WB

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

ELISA 1:5000-10000; FACS 1:100; WB 1:1000

Isotype

IgG

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