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Biotinylated Anti-CCR4 antibody (DMC297) ; IgG1 Chimeric mAb

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1; RANTES; TARC and MCP-1. Chemokines are a group of small polypeptide; structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development; homeostasis; and function of the immune system; and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Product Specifications

Product Name Alternative

CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5

Gene Name

CCR4

UniProt

P51679

Host

Rabbit

Reactivity

Human

Target Antigen

CCR4

Clonality

Monoclonal

Clone

DMC297

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

Flow Cyt 1:100

Isotype

IgG1

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