Biotinylated Anti-TREM2 antibody (DMC223) ; IgG1 Chimeric mAb

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) . Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

Product Name Alternative

PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c

Gene Name

TREM2

UniProt

Q9NZC2

Host

Rabbit

Reactivity

Human

Target Antigen

TREM2

Clonality

Monoclonal

Clone

DMC223

Applications

ELISA; FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.