Biotinylated Anti-IFNAR1 antibody (DMC221) ; IgG1 Chimeric mAb

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases; which in turn phosphorylate several proteins; including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.

Product Specifications

Product Name Alternative

Interferon alpha:beta receptor 1; IFN-R-1; IFN-alpha:beta receptor 1; CRF2-1; Type I interferon receptor 1

Gene Name

IFNAR1

UniProt

P17181

Host

Rabbit

Reactivity

Human

Target Antigen

IFNAR1

Clonality

Monoclonal

Clone

DMC221

Applications

ELISA; FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.