Anti-IFNG antibody (1A2), IgG1 Chimeric mAb

IFNÎ3 is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNÎ3 synthesis is induced by IL-2, FGF-basic, and EGF.

Product Specifications

Product Name Alternative

IFN-gamma; Immune interferon

Gene Name

IFNG

UniProt

P01579

Host

Rabbit

Reactivity

Human

Target Antigen

IFNG

Clonality

Monoclonal

Clone

1A2

Applications

ELISA

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 9% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.