Anti-GUCY2C antibody (6E3), IgG1 Chimeric mAb

This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive) . [provided by RefSeq, Nov 2016]

Product Specifications

Product Name Alternative

DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR

Gene Name

GUCY2C

UniProt

P25092

Host

Rabbit

Reactivity

Human

Target Antigen

GUCY2C

Clonality

Monoclonal

Clone

6E3

Applications

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.