Anti-EGFRVIII antibody (2E12) ; IgG1 Chimeric mAb

Description :Anti-EGFRVIII antibody (2E12) ; IgG1 Chimeric mAbThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Product Specifications

Product Name Alternative

EGFR; RBB; RBB1; ER1; IG61; ENA

UniProt

P00533

Host

Rabbit

Reactivity

Human

Target Antigen

EGFRVIII

Clonality

Monoclonal

Clone

2E12

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.