Anti-ALPP antibody (DMC686) ; IgG1 Chimeric mAb

Description :Anti-ALPP antibody (DMC686) ; IgG1 Chimeric mAbThe protein encoded by this gene is an alkaline phosphatase; a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions; which are required for its enzymatic function. One of the main sources of this enzyme is the liver; and thus; it's one of several indicators of liver injury in different clinical conditions. In pregnant women; this protein is primarily expressed in placental and endometrial tissue; however; strong ectopic expression has been detected in ovarian adenocarcinoma; serous cystadenocarcinoma; and other ovarian cancer cells. [provided by RefSeq; Aug 2020]

Product Specifications

Product Name Alternative

ALP; ALPI; IAP; PALP; PLAP; PLAP-1

UniProt

P05187

Host

Rabbit

Reactivity

Human

Target Antigen

ALPP

Clonality

Monoclonal

Clone

DMC686

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.