Anti-YAP1 antibody (DMC495) ; IgG1 Chimeric mAb

Description :Anti-YAP1 antibody (DMC495) ; IgG1 Chimeric mAbThis gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development; growth; repair; and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

Product Name Alternative

COB1; YAP; YAP2; YAP65; YKI

UniProt

P46937

Host

Rabbit

Reactivity

Human

Target Antigen

YAP1

Clonality

Monoclonal

Clone

DMC495

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.