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Anti-FZD10 antibody (DMC487) ; IgG1 Chimeric mAb

Description :Anti-FZD10 antibody (DMC487) ; IgG1 Chimeric mAbThis gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis; expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq; Jul 2008]

Product Specifications

Product Name Alternative

CD350; FZ-10; Fz10; FzE7; hFz10

UniProt

Q9ULW2

Host

Rabbit

Reactivity

Human

Target Antigen

FZD10

Clonality

Monoclonal

Clone

DMC487

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

FACS 1:100

Isotype

Rabbit/Human Fc chimeric IgG1

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