Anti-CXCR1 antibody (DMC470) ; IgG1 Chimeric mAb

Description :Anti-CXCR1 antibody (DMC470) ; IgG1 Chimeric mAbThe protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8) . It binds to IL8 with high affinity; and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene; IL8RB; a gene encoding another high affinity IL8 receptor; as well as IL8RBP; a pseudogene of IL8RB; form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq; Jul 2008]

Product Specifications

Product Name Alternative

C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; IL8R1; IL8RA; IL8RBA

UniProt

P25024

Host

Rabbit

Reactivity

Human

Target Antigen

CXCR1

Clonality

Monoclonal

Clone

DMC470

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.