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Anti-PRLR antibody (DMC462) ; IgG1 Chimeric mAb

Description :Anti-PRLR antibody (DMC462) ; IgG1 Chimeric mAbThis gene encodes a receptor for the anterior pituitary hormone; prolactin; and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene; which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq; Feb 2011]

Product Specifications

Product Name Alternative

Prolactin receptor; PRL-R

UniProt

P16471

Host

Rabbit

Reactivity

Human

Target Antigen

PRLR

Clonality

Monoclonal

Clone

DMC462

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

Applications Notes

FACS 1:100

Isotype

Rabbit/Human Fc chimeric IgG1

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