Anti-IGFBP7 antibody (DMC422) ; IgG1 Chimeric mAb

Description :Anti-IGFBP7 antibody (DMC422) ; IgG1 Chimeric mAbThis gene encodes a member of the insulin-like growth factor (IGF) -binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307) .

Product Specifications

Product Name Alternative

IBP-7; TAF; IGFBP-rP1; MAC25 protein

UniProt

Q16270

Host

Rabbit

Reactivity

Human

Target Antigen

IGFBP7

Clonality

Monoclonal

Clone

DMC422

Applications

FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.