Anti-IL2RA antibody (DM148), Rabbit mAb
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Product Specifications
Product Name Alternative
IL2RA, CD25, p55, IL2-RA, IL-2-RA
Host
Rabbit
Reactivity
Human
Target Antigen
IL2RA
Clonality
Monoclonal
Clone
DM148
Applications
ELISA, FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Not Sterile
Storage Conditions
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Applications Notes
ELISA 1/5000-10000; FACS 1/100
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