Anti-TNFRSF10B antibody (DM113), Rabbit mAb
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Product Specifications
Product Name Alternative
TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB
Host
Rabbit
Reactivity
Human
Target Antigen
TNFRSF10B
Clonality
Monoclonal
Clone
DM113
Applications
ELISA, FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Not Sterile
Storage Conditions
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Applications Notes
ELISA 1/5000-10000; FACS 1/100
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