Anti-B7-H2 antibody (DM97), Rabbit mAb
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2.The protein is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Product Specifications
Product Name Alternative
ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS, ICOS ligand
Host
Rabbit
Reactivity
Human
Target Antigen
B7-H2
Clonality
Monoclonal
Clone
DM97
Applications
ELISA, FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Not Sterile
Storage Conditions
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Applications Notes
ELISA 1/5000-10000; FACS 1/100
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