Anti-CD27 antibody (DM59), Rabbit mAb
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Product Specifications
Product Name Alternative
CD27, TNFRSF7, S152, T14, Tp55
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD27 (Ala20-Arg191) produced by using human HEK293 cells
Clonality
Monoclonal
Clone
DM59
Applications
ELISA, FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Preservative: 0.1% Procline 300 Constituents: 50% Glycerol; PBS, pH 7.4; 0.1% BSANot Sterile
Shipping Conditions
Delivery in 1-2 weeks
Storage Conditions
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Applications Notes
Recommended Dilutions ELISA 1/5000-10000; FACS 1/100
Isotype
Rabbit IgG
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