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Anti-ACE2 antibody (DM47), Rabbit mAb

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Product Specifications

Product Name Alternative

ACE-2, ACEH, ACE2

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human ACE2 (Gln18-Ser740) produced by using human HEK293 cells

Clonality

Monoclonal

Clone

DM47

Applications

ELISA, FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Components

Preservative: 0.1% Procline 300 Constituents: 50% Glycerol; PBS, pH 7.4; 0.1% BSANot Sterile

Shipping Conditions

Delivery in 1-2 weeks

Storage Conditions

Store at -20°C for 12 months (Avoid repeated freezing and thawing)

Applications Notes

Recommended Dilutions ELISA 1/5000-10000; FACS 1/100

Isotype

Rabbit IgG

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