Anti-CD123 antibody (DM31), Rabbit mAb
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor Alpha chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Product Specifications
Product Name Alternative
IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD123 (Thr19-Arg305) produced by using human HEK293 cells
Clonality
Monoclonal
Clone
DM31
Applications
ELISA, FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Components
Preservative: 0.1% Procline 300 Constituents: 50% Glycerol; PBS, pH 7.4; 0.1% BSANot Sterile
Shipping Conditions
Delivery in 1-2 weeks
Storage Conditions
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Applications Notes
Recommended Dilutions ELISA 1/5000-10000; FACS 1/100
Isotype
Rabbit IgG
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