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Biotinylated Anti-CD123 antibody (DM31), Rabbit mAb

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor ? chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

Product Specifications

Product Name Alternative

IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha

Host

Rabbit

Reactivity

Human

Target Antigen

CD123

Clonality

Monoclonal

Clone

DM31

Applications

ELISA, FACS

Purification

Purified from cell culture supernatant by affinity chromatography

Format

Powder

Components

Not Sterile

Storage Conditions

Store at 2 °C-8 °C for 6 months

Applications Notes

ELISA 1/5000-10000; FACS 1/100

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