Recombinant Anti-Monkeypox B5 Antibody (Clone: MPXV-13)

Expression Host : HEK-293 Reactivity Species : Vaccinia, Variola, Cowpox, Monkeypox, Virus Specificity : MPXV-13 reacts to B5, an EV surface antigen. This antibody also reacts to VACV antigen and lysate, CPXV lysate, MPXV lysate, and VARV antigen and lysate. MPXV-13 weakly binds to VACV purified antigen, VACV and MPXV virus-infected cell lysates, and strongly binds VARV purified antigen and CPXV virus-infected cell lysate. MPXV-13 neutralizes VACV EV plus complement (+C') but not MV, MV+C', or EV. MPXV-13 also binds to CPXV EV+C' but not EV. MPXV-13 does not neutralize MPXV MV, MV+C', EV, or EV+C'.

Product Specifications

Product Name Alternative

MPXV

Host

Human

Immunogen

Sequenced from PBMCs from a donor who had recovered from a naturally-occurring MPXV infection

Clonality

Monoclonal

Clone

MPXV-13

Applications

ELISA

Purification

>=95% monomer by analytical SEC

Components

1.0 mg/mL . This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.

Storage Conditions

Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at >= -70°C. Avoid Repeated Freeze Thaw Cycles.