Phospho-c-Fos (Ser32) (Clone: BA9) rabbit mAb
C-FOS belongs to the Fos family of nuclear oncogenes which include Fos B, Fos-related antigen 1 (FRA1), Fos-related antigen 2 (FRA2) in addition to c-Fos (1) . Activator Protein-1 (AP-1) is formed upon dimerization of Fos proteins with Jun protiens (c-Jun, Jun B, and JunD) (2,3) . AP-1 is considered a transcription factor that binds to TRE/AP-1 elements and activates transcription. ERK5 is involved with c-Fos phosphorylation at Ser32 and Thr232 which increase c-Fos stability and its nuclear translocation.
Product Specifications
Product Name Alternative
Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, G0S7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser32 of human phospho c-Fos
Clonality
Monoclonal
Clone
CFosS32-BA9
Applications
FACS
Format
Purified
Components
1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Storage Conditions
Store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Rabbit IgG1k
Conjugate
Unconjugated
Frequently Asked Questions
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