Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-mTOR (Ser2448) (Clone: E11) rabbit mAb PE Conjugate

MTOR, mammalian target of rapamycin, is a Serine/Threonine protein kinase (1-2) that functions as an amino acid and ATP sensor to balance cell growth and nutrient availability (3-4) . When sufficient nutrients are available, mTOR transmits a positive signal to p70 S6 kinase and participates in the inactivation of 4E-BP1 (5) . mTOR plays a key role in homeostasis and cell growth, and phospho mTOR may be abnormally regulated in tumors. mTOR is a potential target for anti-cancer therapy (6) .

Product Specifications

Product Name Alternative

Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RA

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR

Clonality

Monoclonal

Clone

MTORS2448-E11

Applications

FACS

Components

1X PBS, 0.09% NaN3, 0.2% BSA

Storage Conditions

Store at 2-8°C. Avoid repeated freeze and thaw cycles.

Applications Notes

For flow cytometric staining, the suggested use of this reagent is 5 μL per million cells or 5 μL per 100 μL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.

Isotype

Rabbit IgG1k

Conjugate

PE

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

3-Chloro-1H-pyrazolo[3,4-b]pyridine
268138-01 100 mg

3-Chloro-1H-pyrazolo[3,4-b]pyridine

Sign In for Pricing
View Details
3-Chloro-1H-pyrazolo[3,4-b]pyridine
268138-02 250 mg

3-Chloro-1H-pyrazolo[3,4-b]pyridine

Sign In for Pricing
View Details
3-Chloro-1H-pyrazolo[3,4-b]pyridine
268138-03 500 mg

3-Chloro-1H-pyrazolo[3,4-b]pyridine

Sign In for Pricing
View Details
3-Chloro-1H-pyrazolo[3,4-b]pyridine
268138-04 1 g

3-Chloro-1H-pyrazolo[3,4-b]pyridine

Sign In for Pricing
View Details
3-Chloro-1H-pyrazolo[3,4-b]pyridine
268138-05 2 g

3-Chloro-1H-pyrazolo[3,4-b]pyridine

Sign In for Pricing
View Details
CNTD2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
16508111 3x 1.0 µg

CNTD2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

Sign In for Pricing
View Details