Phospho-MSK1 (Thr581) (Clone: A5) rabbit mAb APC conjugate
MSK1 (mitogen and stress activated protein kinase 1, phospho MSK1) is activated by Erk in response to growth factors and by and p38 in response to cellular stress (1) . MSK1 is similar to RSK1 in that it has two kinase domains and a connecting regulatory linker region (2) . S364/S381 phosphorylation activates RSK1 (3), which is analogous to residues S360 and S376 of MSK1, which may be important for phospho MSK1 activity.
Product Specifications
Product Name Alternative
Ribosomal protein S6 kinase alpha-5, S6K-alpha-5, 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, RPS6KA5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1
Clonality
Monoclonal
Clone
MSK1T581-A5
Applications
FACS
Format
Conjugated
Components
1X PBS, 0.09% NaN3, 0.2% BSA
Storage Conditions
Store at 2-8°C. Avoid repeated freeze and thaw cycles.
Applications Notes
For flow cytometric staining, the suggested use of this reagent is 5 μL per million cells or 5 μL per 100 μL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
Isotype
Rabbit IgG1k
Conjugate
APC
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