Anti-Cytokeratin, Multi (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rKRT/457)
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI<5.7) and basic (pI>6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4) ; 58kDa (CK5) ; 56kDa (CK6) ; 52kDa (CK8) ; 56.5kDa (CK10) ; 53kDa (CK13) and 45kDa (CK18) . This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Product Specifications
Gene Name
Not Known
Gene ID
3851 (CK4) ; 3852 (CK5) ; 3853 (CK6A) ; 3854 (CK6B)
UniProt
P02538 (CK6A) ; P04259 (CK6B) ; P13647 (CK5) ; P19013 (CK4) ; P48668 (CK6C
Host
Mouse
Reactivity
Human
Immunogen
Keratin-enriched preparation from cultured human epithelial cells
Clonality
Monoclonal
Clone
RKRT/457
Applications
IHC
Purification
Protein A/G
Format
Purified
Components
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Applications Notes
Isotype
Mouse IgG1, kappa
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