Recombinant Rabbit Monoclonal Antibody to Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (Clone : TYRP1/1564R)
Selected Variant
12-1044-20
Size: 20 µg
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Product Specifications
Product Name Alternative
Gene Name
TYRP1
Gene ID
7306
UniProt
P17643
Reactivity
Human, Mouse
Immunogen
Recombinant human full-length TYRP1 protein
Target Antigen
Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)
Clonality
Monoclonal
Clone
TYRP1/1564R
Applications
IHC
Purification
Purified Ab with BSA and Azide at 200ug/ml
Format
Purified
Components
200ug/mL of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Rabbit IgG
Price
Frequently Asked Questions
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