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Recombinant Rabbit Monoclonal Antibody to CD15 / FUT4 (Reed-Sternberg Cell Marker) (Clone : FUT4/1478R)

Selected Variant

12-1022-100

Size: 100 µg

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Product Specifications

Product Name Alternative

3 Fucosyl N Acetyl Lactosamine, Alpha (1,3) Fucosyltransferase, Alpha 13 fucosyltransferase FucT, ELAM Ligand Fucosyltransferase, ELFT, FCT3A, Fuc-TIV, Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific, Fucosyltransferase 4, Galactoside 3 L Fucosyltransferase, Lewis X, L

Gene Name

FUT4

Gene ID

2526

UniProt

P22083

Reactivity

Human, Mouse, Rat

Immunogen

Purified human neutrophils

Target Antigen

CD15 / FUT4 (Reed-Sternberg Cell Marker)

Clonality

Monoclonal

Clone

FUT4/1478R

Applications

FACS, IF, IHC

Purification

Purified Ab with BSA and Azide at 200ug/ml

Format

Purified

Components

200ug/mL of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & Azide at 1.0mg/mL.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Flow Cytometry (1-2μg/million cells) ; Immunofluorescence (1-2μg/mL) ; Immunohistochemistry (Formalin-fixed) (1-2μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 8.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)

Isotype

Rabbit IgG

Price

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